Myelosuppressive therapy is indicated for patients at high risk. Hydroxyurea inhibits the enzyme ribonucleoside diphosphate reductase. It is also used to take elimite cream bone marrow activity. There is no clear data on the ability of hydroxyurea to provoke leukemia. However, the possibility of transformation into leukemia exists, although it is small. Patients undergo weekly blood tests. After reaching a steady state, the intervals between blood tests are increased to 2 weeks and then to 4 weeks. If your white blood cell count drops, rate the material 1 2 3 4 5.
What is polycythemia vera and is it treatable? Today we will talk about a blood disease called polycythemia vera. This disease is a pathology in which there is an increased number of red blood cells in the circulating blood. Polycythemia poses a great, sometimes irreversible danger to human life and health, so it is important to recognize the disease by its first signs for timely medical care and competent treatment. Typically, this syndrome is characteristic of people over the age of 50, and is more often diagnosed in males. Let's take a closer look at the disease in all its aspects. etiology, types, diagnosis and main methods of treating polycythemia. General information about the disease.
In modern medicine, polycythemia has several names, for example, Vaquez disease, and it is also sometimes called erythrocytosis. The pathology belongs to the section of chronic leukemia and represents an active increase in the concentration of red blood cells, leukocytes and platelets in the blood; most often, experts classify this disease as a rare type of elimite. Medical statistics say that polycythemia vera is diagnosed annually in only 5 cases per 1 million patients; the development of pathology is usually typical for older men (from 50 to 65 years).
The most dangerous complications of the disease include the risk of developing thrombosis and hemorrhagic strokes, as well as the transition of polycythemia to the acute stage of myeloid leukemia or to the chronic stage of myeloid leukemia. This disease is characterized by a number of reasons, which we will consider below. All causes of erythremia are divided into two types. primary and secondary. In modern medicine, the root causes of this pathology include the following.
Most often, erythremia has a tumor factor, characterized by damage to stem cells produced in the red bone marrow. The result of the destruction of these cells is an increase in the level of red blood cells, which directly leads to disruption of the functioning of the entire body. The disease is malignant, difficult to diagnose and takes a long time to treat, and not always with a positive effect; complex therapy is due to the fact that no treatment methods can affect a stem cell that has undergone a mutation, which has a high ability to divide. Polycythemia vera is characterized by the presence of plethora, this is due to the fact that the concentration of red blood cells in the vascular bed is increased.
